Difference between Sterile and Aseptic

Sterile means the complete absence of viable microorganisms or organisms capable of reproduction. Non-living (bacteria, fungi and viruses)

Sterile means any surface and product contact part free from microbial contamination is said to be sterile. Products free from all pathogens and microorganisms are called sterile products, such as surgical gloves (sterile surgical gloves), small-volume parenteral and large-volume parenteral and ophthalmic products.

Techniques used to remove all harmful microorganisms or pathogens are called sterile techniques.

Aseptic means an area free of pathogenic microorganisms. Limits of microorganisms are present there. An aseptic process prevents contamination by excluding microorganisms.

In a simple example, reduce the number of life forms by washing hands with soap. For practical purposes, if one wants to decontaminate an area, not to sterilize it but to keep it free of bacteria or pathogens for a long time to preserve the product, then follow an aseptic technique to preserve the product. For example, many food cold chains are following this aseptic condition.

Aseptic process for handling sterile (sterile) materials in a controlled environment. Carrying microorganisms to a minimum level.

In any environment where human operators are present, some level of microbial contamination is inevitable. Even the most careful clean-room environment design and operation will not eliminate microbial shedding if human operators are present.

Thus, the expectation of zero contamination in small areas during each aseptic processing operation is technically impossible and thus unrealistic.

If we refer to the classification of areas where sterile products are manufactured, it is better to refer to an aseptic area or a controlled area rather than a sterile area.

Share This Post

Related Articles

© 2024 Pharmaceuticals Index. All rights reserved.