Biomedical science
Biomedical science is a body of science that applies parts of the natural sciences or formal sciences, or both, to the development of knowledge, interventions, or technologies that are used in healthcare or public health. Disciplines such as medical microbiology, clinical virology, clinical epidemiology, ...
Rollar Compaction
Roller compaction is also a tablet manufacturing process, sometimes known as dry granulation that increases flowability.
However, it has several unique properties that make it ideal for roller compaction. An alternative is to mix only the excipient and not the API.
This premix can then be compacted by ...
Production of solid dosage forms
1. Material Handling
In large-scale operations, mechanical devices such as drum lifting and tilting machines and more sophisticated methods of material handling such as screw feed systems, vacuum loading systems and metering pumps become necessary, unlike in the laboratory where materials are simply ...
Antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent to fight against bacterial infections and antibiotic drugs are widely used in the treatment and prevention of such infections. They can either kill bacteria or cause them to ...
Typical Process flow of Generic Drug Development
– Obtain project proposal from project management department
– Perform literature review and request to the TSD/SCM for RLD/ Reference/ Market sample
– Raise requisition for new API, excipients, packaging materials and analytical requirements to TSD/SCM
– Perform RLD/ Reference/ ...
Advantages and Disadvantages of Roller Compaction
Advantages:
1. In general, a major advantage of dry granules over wet granules is the absence of water or any organic solvents. Therefore, this method is particularly attractive for drugs, which are sensitive to moisture or heat.
2. It is suitable for compounds that either have low melting points ...
Pharmacy technician
Pharmacy technicians support the work of pharmacists and other health professionals by performing a variety of pharmacy-related functions, including dispensing prescription drugs and other medical devices to patients and instructing them on their use. They may also perform administrative duties in pharmaceutical ...
Lubricants Used in Pharmaceuticals
Lubricants are used to reduce friction between the moving surfaces of machines. Fractions can heat moving parts. It also helps reduce the load and rust on the machine. Generally, lubricants are prepared with organic and synthetic compounds that are not approved in pharmaceuticals.
Compression machines, ...
Direct compression
Direct compression is the simplest and most cost-effective process where APIs and functional excipients such as filler binders or lubricants are mixed in a screw mixer with pre-mixed powders then directly compressed with a tablet press.
Advantages of direct compression costs are low production is fast ...


