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After the first cephalosporin was discovered in 1945, scientists improved the structure of cephalosporins to make them more effective against a wider range of bacteria. Each time the structure changed, a new “generation” of cephalosporins were made. There are five generations of cephalosporins. Third generation cephalosporins were the third generation of cephalosporins to be developed.
Cephalosporins are a large group of antibiotics derived from the mold Acremonium (previously called Cephalosporium). Cephalosporins are bactericidal (kill bacteria) and work in a similar way to penicillins. They bind to and block the activity of enzymes responsible for making peptidoglycan, an important component of the bacterial cell wall. They are called broad-spectrum antibiotics because they are effective against a wide range of bacteria.
Third generation cephalosporins may be used to treat the following types of infections when caused by susceptible strains of bacteria:
Bacteremia/septicemia
List of Third generation cephalosporins:
Rocephin (Pro)
Generic name: ceftriaxone
Omnicef (Pro)
Generic name: cefdinir
Suprax (Pro)
Generic name: cefixime
Vantin (Pro)
Generic name: cefpodoxime
Spectracef
Generic name: cefditoren
Cedax
Generic name: ceftibuten
Omnicef Omni-Pac
Generic name: cefdinir
Tazicef (Pro)
Generic name: ceftazidime
Fortaz (Pro)
Generic name: ceftazidime
Claforan
Generic name: cefotaxime
Cefobid
Generic name: cefoperazone
Cefizox
Generic name: ceftizoxime
