Stage 1 Filling: Top punch is withdrawn from the die by the upper cam Bottom punch is low inthe die, so powder falls in through the hole and fills the die. The punch-die cavity is made of dieand lower punch. Then the position of lower created the volume of the cavity. This volume isappropriately adjusted ...
Direct compression is the simplest and most cost-effective process where APIs and functional excipients such as filler binders or lubricants are mixed in a screw mixer with pre-mixed powders then directly compressed with a tablet press.
Advantages of direct compression costs are low production is fast ...