What is HVAC ?

It controls Temperature, Humidity and Air quality inside a building. HVAC technology aims to provide thermal comfort and acceptable indoor air quality. HVAC system design is a sub discipline of mechanical engineering, based on the principles of thermodynamics, fluid mechanics, and heat transfer. The HVAC system is an extremely vital concern, which aids to enhance and maintain the quality of drug products. It mainly helps in achieving an optimal temperature, ventilation, and air conditioning in the production areas. The HVAC system design directly impacts prevention and control of cross contamination; and maintains hygienic condition at the work place. Certain pharmaceutical products such as parenteral, bulk drug etc.

In order to achieve a proper cleanliness in the storage and quarantine area, High efficiency particulate air (HEPA) filters are used. They also maintain the aseptic condition in the working area. The efficiency and integrity of the filters that are used in this system must be checked at regular intervals by performing leak test. HEPA filters are the main part of the air handling unit (AHU). The AHU collects the outside fresh air and combines it with the air returning from the cubicles and then supplied the treated air back to the laboratory area. A part of the air exiting from the laboratory rooms is directly exhausted into the atmosphere by an exhaust fan, while the remaining air is directed to the AHU where it is filtered by passing through prefilters which is attached to the medium filters, to remove any entrapped particles and then the same air is conditioned for humidity and temperature control, and this filtered air is passed to the laboratory and other areas by a supply fan at desired pressure. HEPA filers are terminal filter which is attached at the entrance to the clean rooms.

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