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There are five main types of parenteral preparations:
1. Injection
2. Powder for injection
3. Infusion
4. Concentrated solution for injection
5. Implants
1. Injections: Injections are sterile solutions in which the active ingredients are dissolved and made up in water for injection or in a suitable non-aqueous base or a mixture of both if they are mixed.
Injections of suspensions may show sediment but should disperse easily with shaking. The suspension should be stable enough to provide a homogeneous dose with each withdrawal from the container.
2. Infusions: Infusions are sterile aqueous solutions with water as the continuous phase. They are free of pyrogens or bacterial endotoxins, are usually made isotonic with blood, and contain no additional antimicrobial preservatives.
3. Powders for injection: Powders for injection are sterile solids that are dispensed to their final volume when shaken with an appropriate volume of sterile WFI to produce a clear particle-free solution.
4. Concentrated solutions for injection: Concentrated solutions for injection are sterile solutions administered by injection or by intravenous infusion after dilution with water for injection.
5. Implants: Implants are sterile solid preparations of a size and shape suitable for implantation in tissues that release the active ingredient over a long period of time. They are individually filled in sterile containers.
