Guidance on Formulating Compressed Solids

The manufacturing of compressed solids is a complex process, requiring several steps to render powders compressible, yet easily dispersed, and with the active ingredient dissolved when placed at the site of administration.

As a result, the formulations that deliver the drugs to the site of action, while maintaining an appropriate stability profile, are valuable. However, a formulation, as described in this volume, requires an understanding of the manufacturing environment conducive to manufacturing a compliant dosage form. The sections in this chapter highlight some of these considerations that would benefit formulators. The topics of interest are presented in alphabetical order for quick reference.

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