Difference between positive and negative controls in microbiology, so positive control is a control group where you change the dependent variable you will see a positive response whereas in a negative control group, whenever you change the dependent variable you would expect a negative response so this shows that The changes you see are due to changes in the dependent variable and nothing else.
positive control
A positive control is an experimental control that produces a positive result. This excludes the independent variable. However, it exhibits preference outcomes that were predicted from the independent variable.
negative control
Negative controls did not respond to treatment. When conducting studies, negative controls should be developed so that they do not lead to the desired results.